Prophylactic Radiotherapy for Prevention of Heterotopic Ossification After Periacetabular Fractures: A Review of Efficacy and Associated Conditions.

Abstract

Prophylactic radiotherapy (XRT) is a commonly used treatment to decrease heterotopic ossification (HO) in patients with traumatic hip injuries. We conducted a retrospective review of patients at risk for HO who underwent XRT. Of the patients reviewed, 27.3% developed radiographic HO, 11.2% developed symptoms, and 2.0% required resection surgery. Patients were divided into primary (n = 71) and secondary prophylaxis (n = 27) cohorts. In the primary group, 25.0% developed radiographic HO, 5.6% developed symptoms, and 0 required surgery. In the secondary cohort, 33.3% of patients developed new radiographic HO, and 25.9% were symptomatic: four had a Brooker score of 3, and three had a score of 4 (p = 0.03), and 7.4% required surgical resection. (Journal of Surgical Orthopaedic Advances 31(2):113-118, 2022).

• Authors: Joseph S Geller, Paul R Allegra, Crystal S Seldon, Benjamin O Spieler, Lara L Cohen, Spencer W Barnhill, Samuel R Huntley, Stuart Samuels, Lora Wang, Derek Isrow, Alberto De La Zerda, Aaron H Wolfson, Giselle Hernandez, Fernando E Vilella, Raphael L Yechieli
• Journal: Journal of surgical orthopaedic advances (J Surg Orthop Adv) Vol. 31 Issue 2 Pg. 113-118 ( 2022) ISSN: 1548-825X [Print] United States
• PMID: 35820098 (Publication Type: Journal Article, Review)

Topics

• Fractures, Bone (complications, surgery)
• Humans
• Ossification, Heterotopic (etiology, prevention & control)
• Retrospective Studies
• Risk Factors