Abstract | INTRODUCTION AND IMPORTANCE: CASE PRESENTATION: A 23-year-old male presented with a right distal radius fracture. Imaging was suggestive of a Campanacci grade 3 GCT at the distal radius with a pathological fracture. His chest X-ray was normal. He was managed with a dorsal open distal radius curettage and stabilization of the fracture with an external minifixator. Histology confirmed a GCT and adjuvant denosumab therapy was given. The response was satisfactory and the external fixator was removed at 5 months. At 42 months post-treatment, he had satisfactory function with no evidence of recurrence. CLINICAL DISCUSSION: The extensive involvement of the distal radius and local invasion precluded the use of internal fixation after thorough curettage. Therefore, an external minifixator was applied to stabilize the fracture and started on denosumab following oncology opinion. CONCLUSION: External fixation and adjuvant denosumab may be considered as an option in patients who are not suitable for internal fixation. However, cohort studies with long term follow up is necessary before it can be recommended in routine practice.
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Authors | Arulanantham Arulprashanth, Aadil Faleel, Chamikara Palkumbura, Umesh Jayarajah, Rukshan Sooriyarachchi |
Journal | International journal of surgery case reports
(Int J Surg Case Rep)
Vol. 96
Pg. 107342
(Jul 2022)
ISSN: 2210-2612 [Print] Netherlands |
PMID | 35785688
(Publication Type: Journal Article)
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Copyright | Copyright © 2022 The Author(s). Published by Elsevier Ltd.. All rights reserved. |