Stridor due to drug-induced hypokalaemic alkalosis.

Abstract

A 76-year-old on long-term Lasix and Pyrogastrone presented with stridor. This became worse with local irritation, e.g. on coughing or during indirect laryngoscopy. Indirect laryngoscopy showed a narrow glottis with an otherwise normal larynx. Blood investigation showed a low serum potassium with a raised bicarbonate level, and a serum calcium level just within the acceptable normal range. A diagnosis of laryngospasm secondary to drug-induced hypokalaemic alkalosis was made. This was treated with the withdrawal of the above drugs and supplementing potassium orally.

• Authors: S K Sarkar
• Journal: The Journal of laryngology and otology (J Laryngol Otol) Vol. 101 Issue 2 Pg. 197-8 (Feb 1987) ISSN: 0022-2151 [Print] England
• PMID: 3572225 (Publication Type: Case Reports, Journal Article)

Chemical References

• Furosemide
• Carbenoxolone

Topics

• Aged
• Alkalosis (chemically induced, complications)
• Carbenoxolone (adverse effects)
• Furosemide (adverse effects)
• Humans
• Hypokalemia (chemically induced, complications)
• Laryngismus (etiology, physiopathology)
• Male
• Respiratory Sounds (etiology)