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Thalidomide in leprosy--study of 94 cases.

Abstract
Thalidomide has a beneficial effect on type II Lepra reaction especially chronic and recurrent reaction. It helps to minimise steroid dependency. Thalidomide was given to 94 cases of type II lepra reaction, who had not responded to steroids or had repeated reactions. This clinical data was analysed regarding clinical improvement, relapse of reaction, side effects of the drug, etc. The analysis showed that all the patients improved remarkably and steroids could be withdrawn. If the competence of staff using this drug is enhanced, morbidity due to leprosy can considerably be reduced.
AuthorsD A Parikh, R Ganapati, C R Revankar
JournalIndian journal of leprosy (Indian J Lepr) 1986 Oct-Dec Vol. 58 Issue 4 Pg. 560-6 ISSN: 0254-9395 [Print] India
PMID3572098 (Publication Type: Journal Article)
Chemical References
  • Thalidomide
  • Prednisolone
  • Clofazimine
Topics
  • Adolescent
  • Adult
  • Clofazimine (therapeutic use)
  • Humans
  • Leprosy (drug therapy)
  • Male
  • Middle Aged
  • Prednisolone (therapeutic use)
  • Thalidomide (adverse effects, therapeutic use)

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