Single-dose ceftriaxone for chancroid.

Abstract

Men with genital ulcers that were culture positive for Haemophilus ducreyi were treated with intramuscular ceftriaxone and randomized to three different dose regimens. All but 1 of 50 men treated with 1 g of intramuscular ceftriaxone were cured. Similarly, 0.5 and 0.25 g cured 43 of 44 men and 37 of 38 men, respectively. A single dose of 250 mg of intramuscular ceftriaxone is an effective treatment for chancroid.

• Authors: M I Bowmer, H Nsanze, L J D'Costa, J Dylewski, L Fransen, P Piot, A R Ronald
• Journal: Antimicrobial agents and chemotherapy (Antimicrob Agents Chemother) Vol. 31 Issue 1 Pg. 67-9 (Jan 1987) ISSN: 0066-4804 [Print] United States
• PMID: 3566241 (Publication Type: Clinical Trial, Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)

Chemical References

• Ceftriaxone

Topics

• Adult
• Ceftriaxone (administration & dosage, therapeutic use)
• Chancroid (drug therapy)
• Drug Administration Schedule
• Humans
• Injections, Intramuscular
• Male
• Random Allocation