Introduction: In patients who have survived
myocardial infarction,
platelet aggregation inhibitor (TAG) treatment plays an important role in preventing recurrent ischemic events. Objective: to investigate the proportion of patients who received
aspirin,
clopidogrel,
prasugrel and
ticagrelor during the hospitalization and the proportion of patients who continued taking the recommended
therapy during follow-up. All patients treated for
myocardial infarction who had a medical ID number were included in the study. Results: 16 273 patients had ST-elevation (
STEMI) and 20 305 patients had non-ST-elevation (
NSTEMI)
infarction. 80% of patients were hypertensive.
Diabetes mellitus (35%) and impaired renal function (30%) were demonstrated in one in three patients. The TAG treatment recommendation was analysed in 36 578 patients who left the hospital.
Clopidogrel 12.7%,
prasugrel 4.3%,
ticagrelor, 93.9%, 77.7%, 8.3% and 3.2% were found in the
NSTEMI group. For medicines available under special conditions (
prasugrel,
ticagrelor), there were significant differences between centres: the proposal varied between 1.2–4.3% for
prasugrel and 0.3–10.8% for
ticagrelor.
Drug switching events were monitored using the National Institute of Health Insurance Fund database. Pharmacovigilance data were available for 29 405 patients. We considered the longest period in the adherence study, and the grace period was 2 months. Adherence durations were processed using a standard survival analysis toolkit (Kaplan–Meier method). At 1 year after the first switch, 76.1%, 78.3%, and 80.9% of the patients in
clopidogrel,
prasugrel and
ticagrelor were adherents to the recommended treatment. Conclusion: The frequency of use of certain
antiplatelet drugs varies significantly across different intervention centres. More than three-quarters of the patients are adherent to treatment 1 year after starting treatment.