Novel application of absorbable gelatine sponge combined with polyurethane film for dermal reconstruction of wounds with bone or tendon exposure.

Abstract

Trauma, burns, and diabetes result in nonhealing wounds that can cause bone or tendon exposure, a significant health threat. The use of an artificial regeneration template combined with skin grafting as an alternative method to highly invasive flap surgery has been shown to be an effective way to cover full-thickness skin defects with bone or tendon exposure for both functional and aesthetic recovery. However, artificial regeneration templates, such as Pelnac, are overwhelmingly expensive, limiting their clinical use. Here, we demonstrate for the first time that polyurethane film combined with absorbable gelatine sponge, affordable materials widely used for haemostasis, are effective for dermal reconstruction in wounds with bone or tendon exposure. The absorbable gelatine sponge combined with polyurethane film was applied to eight patients, all resulting in adequate granulation that fully covered the exposed bone or tendon. The outcome of absorbable gelatine sponge combined with polyurethane film application indicates that this approach is a potential novel and cost-effective dermal reconstruction strategy for the treatment of severe wounds with bone or tendon exposure.

• Authors: Pan Yu, Nan Hong, Min Chen, Xianbiao Zou
• Journal: International wound journal (Int Wound J) Vol. 20 Issue 1 Pg. 18-27 (Jan 2023) ISSN: 1742-481X [Electronic] England
• PMID: 35510525 (Publication Type: Journal Article)
• Copyright: © 2022 The Authors. International Wound Journal published by Medicalhelplines.com Inc (3M) and John Wiley & Sons Ltd.

Chemical References

• Polyurethanes

Topics

• Humans
• Wound Healing
• Polyurethanes (therapeutic use)
• Skin Transplantation (methods)
• Surgical Flaps
• Tendons
• Skin, Artificial