Ciprofloxacin in the treatment of gonorrhoea and non-gonococcal urethritis.

Abstract

The treatment of gonococcal infections by quinolones is reviewed. Acrosoxacin is effective, but side effects are relatively common. Ciprofloxacin is effective in single dosage against urogenital gonococcal infections, and probably also against rectal and pharyngeal infections. It is effective against infections by penicillinase-producing Neisseria gonorrhoeae. In vitro, ciprofloxacin is active against Chlamydia trachomatis, and preliminary results indicate that this drug may be of value in the treatment of non-gonococcal urethritis and chlamydial infection. No major side effects of ciprofloxacin therapy in patients with these infections have been reported.

• Authors: J D Oriel
• Journal: The Journal of antimicrobial chemotherapy (J Antimicrob Chemother) Vol. 18 Suppl D Pg. 129-32 (Nov 1986) ISSN: 0305-7453 [Print] England
• PMID: 3542944 (Publication Type: Journal Article, Review)

Chemical References

• 4-Quinolones
• Anti-Infective Agents
• Anti-Infective Agents, Urinary
• Quinolines
• Quinolones
• rosoxacin
• Ciprofloxacin
• Norfloxacin

Topics

• 4-Quinolones
• Anti-Infective Agents
• Anti-Infective Agents, Urinary (therapeutic use)
• Chlamydia Infections (drug therapy)
• Chlamydia trachomatis
• Ciprofloxacin (therapeutic use)
• Gonorrhea (drug therapy)
• Humans
• Norfloxacin (therapeutic use)
• Quinolines (therapeutic use)
• Quinolones
• Urethritis (drug therapy)