Treatment of Listeria monocytogenes infection with trimethoprim-sulfamethoxazole: case report and review of the literature.

Abstract

A 55-year-old female recipient of an orthotopic liver transplant, who was receiving azathioprine, prednisone and cyclosporin, developed bacteremia due to Listeria monocytogenes. Because of a penicillin allergy, the patient was treated primarIly with trimethoprim-sulfamethoxazole, to which she responded well. The prior literature on use of trimethoprim-sulfamethoxazole in listeria infections is reviewed, and future recommendations are considered. On the basis of the experience described in this case report as well as a review of the literature, trimethoprim-sulfamethoxazole appears to be an effective treatment of listeria infections.

• Authors: P G Spitzer, S M Hammer, A W Karchmer
• Journal: Reviews of infectious diseases (Rev Infect Dis) 1986 May-Jun Vol. 8 Issue 3 Pg. 427-30 ISSN: 0162-0886 [Print] United States
• PMID: 3523699 (Publication Type: Case Reports, Journal Article, Review)

Chemical References

• Drug Combinations
• Trimethoprim, Sulfamethoxazole Drug Combination
• Trimethoprim
• Sulfamethoxazole

Topics

• Drug Combinations (therapeutic use)
• Female
• Humans
• Immunosuppression Therapy
• Listeriosis (drug therapy)
• Liver Transplantation
• Middle Aged
• Sepsis (drug therapy)
• Sulfamethoxazole (therapeutic use)
• Trimethoprim (therapeutic use)
• Trimethoprim, Sulfamethoxazole Drug Combination