HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Influence of SLO4 on the leucocyte migration inhibiting factor and on the DTH response.

Abstract
This phase I study demonstrates the immunostimulating properties of SLO4 administered by the oral route in the healthy volunteer. Responses to the test of DTH (delayed type hypersensitivity) were enhanced by SLO4 and the production of MIF (migration inhibiting factor) involved in this response was stimulated. These properties could be correlated with the previously demonstrated induction of interferon by SLO4.
AuthorsC Vanderhoven, M Douet, K Mitchell, Y Page, J P Girard
JournalJournal of immunopharmacology (J Immunopharmacol) Vol. 8 Issue 1 Pg. 117-23 ( 1986) ISSN: 0163-0571 [Print] United States
PMID3519780 (Publication Type: Clinical Trial, Comparative Study, Journal Article)
Chemical References
  • Adjuvants, Immunologic
  • Leukocyte Migration-Inhibitory Factors
  • Lymphokines
Topics
  • Adjuvants, Immunologic (administration & dosage, pharmacology)
  • Administration, Oral
  • Clinical Trials as Topic
  • Dose-Response Relationship, Drug
  • Escherichia coli
  • Humans
  • Hypersensitivity, Delayed (immunology)
  • Kinetics
  • Klebsiella pneumoniae
  • Leukocyte Migration-Inhibitory Factors (blood)
  • Lymphokines (blood)
  • Skin Tests

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: