Abstract | BACKGROUND/AIMS: METHODS: Using nationally representative data from the Korean National Health Insurance System, we enrolled 140,164 subjects without ESRD at enrolment who underwent PCI between 2010 and 2015, and were followed-up until 2017. Patients were stratified into five levels based on their baseline BMI and six levels based on their WC with 5-cm increments. BMI and WC were measured at least 2 years prior to PCI. The primary outcome was the development of ESRD. RESULTS: During a median follow-up of 5.4 years, 2,082 (1.49%) participants developed ESRD. The underweight group (hazard ratio [HR], 1.331; 95% confidence interval [CI], 0.955 to 1.856) and low WC (< 80/< 75) (HR, 1.589; 95% CI, 1.379 to 1.831) showed the highest ESRD risk and the BMI 25 to 30 group showed the lowest ESRD risk (HR, 0.604; 95% CI, 0542 to 0.673) in all participants after adjusting for all covariates. In the subgroup analysis for diabetes mellitus (DM) duration, WC < 85/80 cm (men/women) increased ESRD risk in only the DM group (DM < 5 years and DM ≥ 5 years) compared to the reference group (85-90/80-85 of WC), but not the normal or impaired fasting glucose group. CONCLUSION: Low WC prior to PCI showed an increased ESRD risk in patients with DM undergoing PCI as compared to those without DM.
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Authors | Eun Hui Bae, Sang Yup Lim, Eun Mi Yang, Tae Ryom Oh, Hong Sang Choi, Chang Seong Kim, Seong Kwon Ma, Bongseong Kim, Kyung-Do Han, Soo Wan Kim |
Journal | The Korean journal of internal medicine
(Korean J Intern Med)
Vol. 37
Issue 3
Pg. 639-652
(05 2022)
ISSN: 2005-6648 [Electronic] Korea (South) |
PMID | 35143719
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Topics |
- Body Mass Index
- Cohort Studies
- Female
- Humans
- Kidney Failure, Chronic
(diagnosis, epidemiology, therapy)
- Male
- Percutaneous Coronary Intervention
(adverse effects)
- Republic of Korea
(epidemiology)
- Risk Factors
- Waist Circumference
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