Abstract |
The serological response to treponemal infections in men before and after specific treatment is analyzed. From the described observations several consequences and possibilities for a specific immunological diagnosis are discussed. In particular, it is shown that early diagnosis of syphilis in need of treatment can be achieved by demonstration of T pallidum-specific IgM antibodies. Finally, new insights into the role of antibody correlations between serum and cerebrospinal fluid are mentioned that have established the detection of asymptomatic neurosyphilis.
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Authors | F Müller |
Journal | Diagnostic immunology
(Diagn Immunol)
Vol. 4
Issue 1
Pg. 1-9
( 1986)
ISSN: 0735-3111 [Print] United States |
PMID | 3514069
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't, Review)
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Chemical References |
- Antibodies, Bacterial
- Immunoglobulin G
- Immunoglobulin M
- Penicillins
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Topics |
- Antibodies, Bacterial
(analysis, biosynthesis)
- Antibody Specificity
- Humans
- Immunoglobulin G
(analysis, biosynthesis)
- Immunoglobulin M
(analysis, biosynthesis)
- Infant
- Infant, Newborn
- Male
- Neurosyphilis
(diagnosis, immunology)
- Penicillins
(therapeutic use)
- Syphilis
(drug therapy, immunology)
- Syphilis Serodiagnosis
(methods)
- Syphilis, Congenital
(diagnosis)
- Treponema pallidum
(immunology)
- Treponemal Infections
(diagnosis, drug therapy, immunology)
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