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[Controlled study of the analgesic effect and tolerability of buprenorphine in cancer patients].

Abstract
The analgesic efficacy and tolerability of a morphine agonist-antagonist buprenorphine are evaluated. The drug is compared to pentazocin. For this purpose, the drugs were randomly administered to 42 patients suffering from pain caused by advanced cancer. Buprenorphine demonstrated a significantly higher analgesic effect than pentazocin and was better tolerated.
AuthorsD Dini, T Fassio, A Gottlieb, M Gini
JournalMinerva medica (Minerva Med) Vol. 77 Issue 3-4 Pg. 93-104 (Jan 28 1986) ISSN: 0026-4806 [Print] Italy
Vernacular TitleStudio controllato sull'effetto analgesico e sulla tollerabilità della buprenorfina, in pazienti affetti da neoplasia.
PMID3511410 (Publication Type: Clinical Trial, Comparative Study, English Abstract, Journal Article, Randomized Controlled Trial)
Chemical References
  • Morphinans
  • Buprenorphine
  • Pentazocine
Topics
  • Buprenorphine (adverse effects, therapeutic use)
  • Clinical Trials as Topic
  • Drug Evaluation
  • Female
  • Humans
  • Male
  • Morphinans (therapeutic use)
  • Neoplasms (drug therapy)
  • Pain, Intractable (drug therapy)
  • Pentazocine (adverse effects, therapeutic use)

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