Treatment of multiple intestinal helminthiasis with oxantel and pyrantel.

Abstract

32 elementary school children were treated for multiple intestinal helminthiasis (ascariasis, trichuriasis and hookworm infections) with a combination of the pamoate salts of oxantel and pyrantel in a dose of 15 to 20mg/kg body weight of each in 1 daily dose for 3 consecutive days. The cure rate for ascariasis was 96.7%, and 84.4% for both trichuriasis and hookworm infections. 68.7% were completely cured of all 3 helminths. However, among those not completely cured, only 1 species of the previous 3 infecting helminths was present after treatment and then with a very marked reduction in egg count.

• Authors: E G Garcia
• Journal: Drugs (Drugs) Vol. 15 Suppl 1 Pg. 70-2 ( 1978) ISSN: 0012-6667 [Print] New Zealand
• PMID: 350568 (Publication Type: Clinical Trial, Journal Article)

Chemical References

• Drug Combinations
• Pyrimidines
• Styrenes
• Pyrantel

Topics

• Child
• Clinical Trials as Topic
• Drug Combinations
• Helminthiasis (drug therapy, parasitology)
• Humans
• Intestinal Diseases, Parasitic (drug therapy, parasitology)
• Pyrantel (adverse effects, therapeutic use)
• Pyrimidines (therapeutic use)
• Styrenes (therapeutic use)