[A Case of Improvement by SOX Therapy for DIC Caused by Gastric Cancer].

Abstract

Disseminated intravascular coagulation(DIC)has a poor prognosis in gastric cancer. The patient was a 78-year-old man. He had been diagnosed with Stage Ⅳ gastric cancer. Before chemotherapy, thrombocytopenia and elevated D-dimer occurred, and we diagnosed DIC. We started SOX therapy to treat gastric cancer with DIC. DIC improved on the 10th day after the onset of DIC. But developed DIC again on the 21st day. We started SOX therapy again. However, the DIC did not improve. The patient died 32 days after the initial DIC. Oxaliplatin regimen may be a potential treatment for DIC.

• Authors: Naoto Fujimoto, Kazuki Odagiri, Yoshitomo Yanagimoto, Kozo Noguchi, Hiroshi Takeyama, Yozo Suzuki, Shingo Noura, Junzo Shimizu, Tomono Kawase, Hiroshi Imamura, Keizo Dono
• Journal: Gan to kagaku ryoho. Cancer & chemotherapy (Gan To Kagaku Ryoho) Vol. 48 Issue 13 Pg. 1892-1894 (Dec 2021) ISSN: 0385-0684 [Print] Japan
• PMID: 35045438 (Publication Type: Case Reports, Journal Article)

Topics

• Aged
• Antineoplastic Combined Chemotherapy Protocols (therapeutic use)
• Disseminated Intravascular Coagulation (drug therapy, etiology)
• Humans
• Male
• Stomach Neoplasms (complications, drug therapy)
• Thrombocytopenia