Abstract | BACKGROUND: CASE: We report a clinical case of a 57 year-old woman, with type I HAE, scheduled for total laparoscopic hysterectomy under general endotracheal anesthesia, which was done successfully without inducing airway edema. Danazol, which increases liver synthesis of C1-INH, was administered and fresh frozen plasma (FFP), which contained C1-INH, was transfused after induction. CONCLUSIONS: For HAE patients, the greatest concern is that general anesthesia can induces upper airway edema by direct mucosal irritation by the endotracheal tube. The perioperative management should include both prophylactic increase of C1-INH production and on-demand administration of C1-INH or FFP.
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Authors | Yun-Sic Bang, Jaeho Cho, Chunghyun Park |
Journal | Anesthesia and pain medicine
(Anesth Pain Med (Seoul))
Vol. 17
Issue 2
Pg. 235-238
(Apr 2022)
ISSN: 2383-7977 [Electronic] Korea (South) |
PMID | 34991189
(Publication Type: Case Reports)
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