[Therapeutic effect of Trental in diabetic angiopathy].

Abstract

The effect of pentoxiphyline substance--Trental, production of Höchst, was studied in 37 diabetics (12 females and 25 males) aged from 36 to 78. Besides according to clinical manifestations, the therapeutic effect was objectivized in dynamics through the oscillography "Gesenius-Keller", double-rheography "Schufrid", skin thermometer--Tastotherm P 60 "Braun" and 6-canal ECG apparatus "Hellige". Favourable results, evaluated according to all mentioned methods were found in 89.2 per cent of the treated 37 patients; excellent effect in 15 of them 40.5%); very good--in 8 (21.6%); good--in 10 (27.1%) 1 and without effect--only 4 patients (10.8%). Trental is concluded to deserve a wide application in the clinical practice for the peripheral diabetic angiopathy treatment in patients with diabetes mellitus.

• Authors: L Pampulov, P Kolarov, N Veleva
• Journal: Vutreshni bolesti (Vutr Boles) Vol. 17 Issue 2 Pg. 66-72 ( 1978) ISSN: 0506-2772 [Print] Bulgaria
• Vernacular Title: Prouchvane na lechebniia efekt na trentala vurkhu diabetnata angiopatiia.
• PMID: 349882 (Publication Type: Clinical Trial, English Abstract, Journal Article)

Chemical References

• Theobromine
• Pentoxifylline

Topics

• Adult
• Aged
• Clinical Trials as Topic
• Diabetic Angiopathies (drug therapy)
• Drug Evaluation
• Electrocardiography
• Female
• Humans
• Male
• Middle Aged
• Pentoxifylline (administration & dosage, therapeutic use)
• Plethysmography, Impedance
• Skin Temperature (drug effects)
• Theobromine (analogs & derivatives)