Abstract |
Bentiromide test (BT) has been recently approved in the United States for screening patients with chronic pancreatitis for exocrine insufficiency. A few reports have suggested that the rice flour breath hydrogen test (RFBHT)--i.e., breath hydrogen analysis after rice flour ingestion--may also be useful in diagnosing exocrine pancreatic insufficiency. We conducted this study to compare the diagnostic value of these two tests in chronic alcoholic (n = 14) and nutritional or tropical (n = 6) pancreatitis. False-positive results were not noted with either of these two tests in 12 healthy volunteers. BT was positive in 28.6% of patients with chronic alcoholic pancreatitis and in 16.7% of patients with tropical pancreatitis. In comparison, RFBHT was almost twice as sensitive as BT in detecting insufficiency in patients with alcoholic pancreatitis (50 vs. 28.6%) and four times as sensitive in patients with tropical pancreatitis (66.7 vs. 16.7%). Only one patient in our study had a positive BT but a negative RFBHT. We recommend RFBHT as a simple, safe, and inexpensive test in screening patients for exocrine pancreatic insufficiency.
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Authors | V P Patel, N K Jain, N Agarwal, P J GeeVarghese, C S Pitchumoni |
Journal | Pancreas
(Pancreas)
Vol. 1
Issue 2
Pg. 172-5
( 1986)
ISSN: 0885-3177 [Print] United States |
PMID | 3494992
(Publication Type: Comparative Study, Journal Article)
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Chemical References |
- Aminobenzoates
- para-Aminobenzoates
- bentiromide
- Hydrogen
- 4-Aminobenzoic Acid
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Topics |
- 4-Aminobenzoic Acid
(urine)
- Adult
- Alcoholism
(complications)
- Aminobenzoates
- Breath Tests
(methods)
- Exocrine Pancreatic Insufficiency
(diagnosis)
- False Positive Reactions
- Female
- Humans
- Hydrogen
(analysis)
- Male
- Middle Aged
- Oryza
- Pancreatitis
(diagnosis, etiology)
- para-Aminobenzoates
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