Background and Objectives: ABO blood types have been implicated as potential risk factors for various hemorrhagic diseases. No study has investigated the association between gastroesophageal variceal
bleeding and ABO blood types. We aimed to evaluate the impact of ABO blood types on mortality and
bleeding risk in acute gastroesophageal variceal
bleeding. Materials and Methods: This is a retrospective observational study. Patients presenting with acute gastroesophageal
varices bleeding diagnosed by endoscopy were enrolled, and were divided by blood type into a type O group and non-type O group. The outcomes were death within 30 days and the proportion of further
bleeding. We used generalized linear mixed-effects models to analyze the outcomes. Results: A total of 327 patients and 648 records of emergency room visits were included. The 30-day mortality was 14.8% (21 of 142 patients) in the type O group, and 16.2% (30 of 185 patients) in the non-type O group (p = 0.532). Further
bleeding within 30 days occurred in 34 cases (12.6%) in the type O group, and in 26 cases (6.9%) in the non-type O group (p = 0.539). Conclusions: There was no significant difference in
blood transfusion volume in 24 h, recurrent
bleeding rates, or mortality between patients with blood type O and those with non-type O.