Treatment of cutaneous T-cell lymphoma with the arotinoid Ro 13-6298.

Abstract

Mycosis fungoides is a neoplasia immunologically defined as a cutaneous T cell lymphoma. It is an uncommon, chronic, and usually fatal disease that runs a progressive multistaged course. The present study describes a case of mycosis fungoides, limited to the skin, which was successfully controlled with the arotinoid Ro 13-6298. Review of the role of retinoids in dermatology and oncology is presented with a special emphasis on the arotinoid.

• Authors: J Tousignant, G P Raymond, M J Light
• Journal: Journal of the American Academy of Dermatology (J Am Acad Dermatol) Vol. 16 Issue 1 Pt 2 Pg. 167-71 (Jan 1987) ISSN: 0190-9622 [Print] United States
• PMID: 3493269 (Publication Type: Case Reports, Journal Article)

Chemical References

• Antineoplastic Agents
• Benzoates
• Retinoids
• Etretinate
• ethyl-p-((E)-2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthyl)-1-propenyl)benzoic acid

Topics

• Antineoplastic Agents (therapeutic use)
• Benzoates (therapeutic use)
• Drug Therapy, Combination
• Etretinate (adverse effects, therapeutic use)
• Female
• Humans
• Lymphoma (drug therapy)
• Middle Aged
• Mycosis Fungoides (drug therapy)
• PUVA Therapy (adverse effects)
• Retinoids (therapeutic use)
• Skin Neoplasms (drug therapy)
• T-Lymphocytes