Ciprofloxacin and co-trimoxazole in urinary tract infection.

Abstract

Seventy-five hospital inpatients with bacteriologically confirmed urinary tract infections were allocated to treatment with ciprofloxacin 100 mg, ciprofloxacin 250 mg or co-trimoxazole 960 mg, all given orally twice a day for five days. The patients were generally elderly, with many complicating factors including indwelling catheters; 24% of the infections were caused by Pseudomonas aeruginosa. The cure rates at 28 days were 94%, 88% and 87%, respectively. Side effects were few and minor. Ciprofloxacin appears to be an effective and safe orally-administrable treatment even for complicated urinary tract infection.

• Authors: A H Williams, R N Grüneberg
• Journal: The Journal of antimicrobial chemotherapy (J Antimicrob Chemother) Vol. 18 Suppl D Pg. 107-10 (Nov 1986) ISSN: 0305-7453 [Print] England
• PMID: 3492487 (Publication Type: Clinical Trial, Comparative Study, Controlled Clinical Trial, Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Anti-Infective Agents, Urinary
• Drug Combinations
• Ciprofloxacin
• Trimethoprim, Sulfamethoxazole Drug Combination
• Trimethoprim
• Sulfamethoxazole

Topics

• Adult
• Aged
• Aged, 80 and over
• Anti-Infective Agents, Urinary (therapeutic use)
• Ciprofloxacin (therapeutic use)
• Drug Combinations (therapeutic use)
• Female
• Humans
• Male
• Middle Aged
• Random Allocation
• Sulfamethoxazole (therapeutic use)
• Trimethoprim (therapeutic use)
• Trimethoprim, Sulfamethoxazole Drug Combination
• Urinary Tract Infections (drug therapy)