Confined placental mosaicism of trisomy 6 detected through genome-wide NIPT was associated with placental abruption.

Abstract

Confined placental mosaicism (CPM) leads to discordant noninvasive prenatal testing (NIPT) results. We describe a very rare case of CPM of trisomy 6 detected through genome-wide NIPT. This case was associated with placental abruption, which might suggest an association between certain types of CPM detected by NIPT and pregnancy complications.

• Authors: Miyuki Nishiyama, Seiji Wada, Fuyuki Hasegawa, Yohji Uehara, Mamoru Ozaki, Kenichiro Hata, Yushi Ito, Haruhiko Sago
• Journal: Clinical case reports (Clin Case Rep) Vol. 9 Issue 12 Pg. e05155 (Dec 2021) ISSN: 2050-0904 [Print] England
• PMID: 34917372 (Publication Type: Case Reports)
• Copyright: © 2021 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd.