Unusual anaphylatoxin dynamics after head injury--case report.

Abstract	The case reported exemplifies a clinical picture markedly at variance with the chronology of symptoms and laboratory findings generally held to be typical in patients with post-traumatic shock. During a protracted clinical course this young man with a skull fracture and epidural haematoma experienced profound hypotension and adult respiratory distress syndrome (ARDS) well in advance of marked fourfold rise of circulating peripheral C3a desArg anaphylatoxin levels. This raises a note of caution with regard to diagnostic and/or therapeutic decisions based on anaphylatoxin assessment of neurosurgical trauma patients at risk of ARDS.
Authors	D Moskopp, A Löcherbach-Zawadzky
Journal	Neurochirurgia (Neurochirurgia (Stuttg)) Vol. 29 Issue 5 Pg. 203-5 (Sep 1986) ISSN: 0028-3819 [Print] Germany
PMID	3491334 (Publication Type: Case Reports, Journal Article)
Chemical References	Anaphylatoxins Complement C3 Peptides Complement C3a
Topics	Adult Anaphylatoxins (metabolism) Brain Edema (immunology) Complement Activation Complement C3 (metabolism) Complement C3a Hematoma, Epidural, Cranial (immunology, surgery) Humans Male Peptides (metabolism) Postoperative Complications (blood) Prognosis Reoperation Skull Fractures (immunology, surgery)

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