Abstract |
Hydrocortisone valerate cream (0.2 percent) was evaluated in three controlled clinical trials involving a total of sixty-eight patients with atopic dermatitis. This new nonfluorinated steroid was found to be as effective as the fluorinated beta-methasone valerate cream (0.1 percent) and significantly more effective than hydrocortisone cream (0.1 percent) and the placebo cream base. All studies were double-blind, paired comparisons, utilizing application of the medications three times a day for up to four weeks or until clearing occurred.
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Authors | H L Roth, E P Brown |
Journal | Cutis
(Cutis)
Vol. 21
Issue 5
Pg. 695-8
(May 1978)
ISSN: 0011-4162 [Print] United States |
PMID | 348406
(Publication Type: Clinical Trial, Comparative Study, Controlled Clinical Trial, Journal Article, Randomized Controlled Trial)
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Chemical References |
- Ointments
- Steroids, Fluorinated
- Valerates
- Hydrocortisone
|
Topics |
- Administration, Topical
- Adolescent
- Adult
- Aged
- Child
- Child, Preschool
- Clinical Trials as Topic
- Dermatitis, Atopic
(drug therapy)
- Double-Blind Method
- Female
- Humans
- Hydrocortisone
(analogs & derivatives, therapeutic use)
- Infant
- Infant, Newborn
- Male
- Middle Aged
- Ointments
- Steroids, Fluorinated
(therapeutic use)
- Time Factors
- Valerates
(therapeutic use)
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