Papillary necrosis associated with rifampicin therapy.

Abstract	We report a patient who developed progressive renal failure following 13 months of rifampicin therapy for renal tuberculosis. The renal function continued to deteriorate despite the discontinuation of rifampicin. Renal pathology did not demonstrate any evidence of tuberculosis of the kidney but revealed the unique pathological finding of glomerulosclerosis, granulomatous interstitial nephritis, and extensive papillary necrosis.
Authors	F M Lai, K N Lai, Y W Chong
Journal	Australian and New Zealand journal of medicine (Aust N Z J Med) Vol. 17 Issue 1 Pg. 68-70 (Feb 1987) ISSN: 0004-8291 [Print] Australia
PMID	3476051 (Publication Type: Case Reports, Journal Article)
Chemical References	Rifampin
Topics	Adult Female Glomerulosclerosis, Focal Segmental (chemically induced) Humans Kidney Papillary Necrosis (chemically induced) Nephritis, Interstitial (chemically induced) Rifampin (adverse effects, therapeutic use) Tuberculosis, Renal (drug therapy) Uremia (chemically induced)

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