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[Current treatment of osteoradionecrosis].

Abstract
Conventional treatment of osteoradionecrosis of mandible is by antibiotics combined if necessary with a hemimandibulectomy. A method is proposed which reduces bone excision to infected and necrotic tissue while respecting mandibular continuity. The bone remaining is covered by a flap taken from a distant region. Five cases treated in this way are reported. When mandibular continuity has to be interrupted to suppress infected foci, immediate repair is performed using an osteo-musculo-cutaneous flap, and six cases treated by this method are reported. A part from their mechanical covering and reconstructing roles these well vascularized flaps improve vitality of tissues they enclose, including the mandibular bone.
AuthorsJ P Lagier, J L Blanc, A Lachard, F Cheynet, P Rakotobe, J Lachard
JournalRevue de stomatologie et de chirurgie maxillo-faciale (Rev Stomatol Chir Maxillofac) Vol. 87 Issue 5 Pg. 311-4 ( 1986) ISSN: 0035-1768 [Print] France
Vernacular TitleLe traitement actuel de l'ostéoradionécrose.
PMID3467411 (Publication Type: English Abstract, Journal Article)
Chemical References
  • Metronidazole
  • Penicillin G
Topics
  • Combined Modality Therapy
  • Drug Therapy, Combination
  • Humans
  • Mandible (surgery)
  • Mandibular Diseases (therapy)
  • Metronidazole (administration & dosage)
  • Osteoradionecrosis (therapy)
  • Penicillin G (administration & dosage)
  • Premedication
  • Radiation Injuries (therapy)
  • Surgical Flaps

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