Features of myocardial injury detected by cardiac magnetic resonance in a patient with desmin-related restrictive cardiomyopathy.

Abstract

Myocardial fibrosis detected by cardiac magnetic resonance (CMR) has been reported in patients with desmin-related myopathy, although its characteristics remain unclear. Here, we describe a case of desmin-related restrictive cardiomyopathy wherein CMR imaging revealed myocardial oedema, ischaemia, and fibrosis in the left ventricle; the different types and processes of myocardial injury were detected by CMR. Middle wall left ventricular enhancement may be a feature of late gadolinium enhancement, and the lateral wall is often involved in cases of myocardial injury. CMR is useful for the early detection of cardiac involvement and the prediction of prognosis in patients diagnosed with desmin-related myopathy.

• Authors: Zixian Chen, Rui Li, Yongxiang Wang, Liang Cao, Chen Lin, Feng Liu, Rui Hu, Jiang Nan, Xin Zhuang, Xiande Lu, Guangxian Nan, Guocui Hu, Jingmei Xue, Yaping Zhang, Jing Xiao, Yali Yao, Shunlin Guo, Junqiang Lei
• Journal: ESC heart failure (ESC Heart Fail) Vol. 8 Issue 6 Pg. 5560-5564 (12 2021) ISSN: 2055-5822 [Electronic] England
• PMID: 34612024 (Publication Type: Case Reports, Journal Article, Research Support, Non-U.S. Gov't)
• Copyright: © 2021 The Authors. ESC Heart Failure published by John Wiley & Sons Ltd on behalf of European Society of Cardiology.

Chemical References

• Contrast Media
• Desmin
• Gadolinium

Topics

• Cardiomyopathies (diagnosis)
• Cardiomyopathy, Restrictive (diagnosis)
• Contrast Media
• Desmin
• Female
• Gadolinium
• Humans
• Magnetic Resonance Imaging, Cine
• Magnetic Resonance Spectroscopy
• Muscular Dystrophies (diagnosis)
• Young Adult