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Vecabrutinib inhibits B-cell receptor signal transduction in chronic lymphocytic leukemia cell types with wild-type or mutant Bruton tyrosine kinase.

AuthorsBurcu Aslan, Stefan Edward Hubner, Judith A Fox, Pietro Taverna, William G Wierda, Steven M Kornblau, Varsha Gandhi
JournalHaematologica (Haematologica) Vol. 107 Issue 1 Pg. 292-297 (01 01 2022) ISSN: 1592-8721 [Electronic] Italy
PMID34498444 (Publication Type: Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't)
Chemical References
  • Protein Kinase Inhibitors
  • Receptors, Antigen, B-Cell
  • Agammaglobulinaemia Tyrosine Kinase
Topics
  • Agammaglobulinaemia Tyrosine Kinase
  • Humans
  • Leukemia, Lymphocytic, Chronic, B-Cell (drug therapy, genetics, metabolism)
  • Protein Kinase Inhibitors (pharmacology, therapeutic use)
  • Receptors, Antigen, B-Cell (genetics, metabolism)
  • Signal Transduction

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