Effect of activated charcoal on endotoxin adsorption. Part I. An in vitro study.

Abstract

An in vitro study by using cross-linked agarose coated activated charcoal (CAAC-II) as adsorbent was conducted. Endotoxin was quantitatively measured by chromogenic method of limulus lysate test. Results of the study demonstrated that endotoxin was fairly efficiently removed by CAAC-II. It may therefore be possible for effective adsorption of endotoxin in vivo studies and warrant further experimental study for CAAC-II hemoperfusion in clinical endotoxemia.

• Authors: X N Du, Z Niu, G Z Zhou, Z M Li
• Journal: Biomaterials, artificial cells, and artificial organs (Biomater Artif Cells Artif Organs) Vol. 15 Issue 1 Pg. 229-35 ( 1987) ISSN: 0890-5533 [Print] United States
• PMID: 3449139 (Publication Type: Journal Article)

Chemical References

• Endotoxins
• Charcoal

Topics

• Adsorption
• Charcoal
• Endotoxins (blood, isolation & purification)
• Hemoperfusion
• Humans
• In Vitro Techniques