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Sulfamethoxazole stone in a patient with extensive history of urolithiasis and recurrent urinary tract infections.

Abstract
Although rare, sulfamethoxazole-induced urolithiasis has been reported in patients taking trimethoprim-sulfamethoxazole (TMP/SMX). We present the case of a 79-year-old female who formed sulfamethoxazole stones in the setting of chronic indwelling catheterization with recurrent urinary tract infections (UTIs). The patient was a recurrent stone former with five prior stone composition analyses over a 10-year period varying from calcium phosphate to calcium oxalate, to struvite. We highlight the need for further investigation of this phenomenon given the frequent use of TMP/SMX in stone formers with recurrent infections.
AuthorsAbbie M Chase, Laena Hines, Elizabeth Ellis, Rajat Jain, Scott O Quarrier
JournalUrology case reports (Urol Case Rep) Vol. 39 Pg. 101812 (Nov 2021) ISSN: 2214-4420 [Print] United States
PMID34466388 (Publication Type: Case Reports)
Copyright© 2021 Published by Elsevier Inc.

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