Multiple forms of bovine pepsinogen: isolation and identification in serum from calves with ostertagiasis.

Abstract

By using fast protein liquid chromatography (FPLC) a new form of bovine pepsinogen has been identified. Compared with the previously isolated pepsinogen (PG I) the new pepsinogen (PG II) is less mobile on agarose electrophoresis, is eluted earlier from an anion-exchange column and is 30 times less abundant. Agarose electrophoresis identified PG I in the serum of calves given third stage Ostertagia ostertagi larvae, while FPLC identified both PG I and PG II in such serum.

• Authors: P D Eckersall, J Macaskill, Q A McKellar, K L Bryce
• Journal: Research in veterinary science (Res Vet Sci) Vol. 43 Issue 3 Pg. 279-83 (Nov 1987) ISSN: 0034-5288 [Print] England
• PMID: 3444973 (Publication Type: Comparative Study, Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Pepsinogens

Topics

• Abomasum (analysis)
• Animals
• Cattle
• Cattle Diseases (blood, enzymology, parasitology)
• Chromatography, Gel
• Chromatography, Liquid
• Electrophoresis, Agar Gel
• Ostertagiasis (enzymology, veterinary)
• Pepsinogens (analysis, blood, isolation & purification)
• Trichostrongyloidiasis (veterinary)