Abstract | BACKGROUND AND AIMS: METHODS: The data of hepatocellular carcinoma patients undergoing curative hepatectomy was reviewed. Those with adjuvant transarterial chemotherapy were matched with those without using propensity score analysis, by tumour size and number, indocyanine green retention rate, disease staging and Child-Pugh grading. The groups were compared. RESULTS: Eighty-seven patients with hepatocellular carcinoma who underwent hepatectomy received adjuvant transarterial chemotherapy (TAC group), and were matched with 870 patients who did not (no-TAC group). The groups were largely comparable in patient and disease characteristics, but the TAC group experienced more blood loss, higher transfusion rates, narrower margins and more positive margins. The two groups were found to be comparable in disease-free and overall survival rates. In margin-positive patients, those given TAC survived longer than those without, and margin-positive patients in the TAC group had overall survival rates similar to margin-negative patients in the no-TAC group. CONCLUSIONS:
|
Authors | Alvina Jada Fok, Wong Hoi She, Ka Wing Ma, Simon H Y Tsang, Wing Chiu Dai, Albert C Y Chan, Chung Mau Lo, Tan To Cheung |
Journal | Langenbeck's archives of surgery
(Langenbecks Arch Surg)
Vol. 407
Issue 1
Pg. 245-257
(Feb 2022)
ISSN: 1435-2451 [Electronic] Germany |
PMID | 34406489
(Publication Type: Journal Article)
|
Copyright | © 2021. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature. |
Topics |
- Carcinoma, Hepatocellular
(drug therapy, surgery)
- Chemoembolization, Therapeutic
- Chemotherapy, Adjuvant
- Hepatectomy
- Humans
- Liver Neoplasms
(drug therapy, surgery)
- Neoplasm Recurrence, Local
(therapy)
- Propensity Score
- Retrospective Studies
|