Abstract | BACKGROUNDS/AIMS: Surgical resection is the only curative treatment for biliary tract cancers; however, most patients undergo palliative chemotherapy because they are contraindicated for surgery. Conversion surgery, a treatment strategy for downsizing chemotherapy and subsequent surgical resection, is feasible for initially unresectable biliary tract cancers following the introduction of effective chemotherapeutic agents. METHODS: Patients initially diagnosed with unresectable biliary tract cancers, and treated with conversion surgery after palliative chemotherapy between 2013 and 2019, were reviewed retrospectively. RESULTS: CONCLUSIONS: Conversion surgery represents a therapeutic alternative for specific cases of unresectable biliary tract cancers. Palliative chemotherapy for initially unresectable biliary tract cancers is recommended for downsizing the tumor and expanding the indications for surgery. Further studies and clinical trials are required to develop new and effective chemotherapeutic regimens.
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Authors | Moon Young Oh, Hongbeom Kim, Yoo Jin Choi, Yoonhyeong Byun, Youngmin Han, Jae Seung Kang, Heeju Sohn, Jung Min Lee, Wooil Kwon, Jin-Young Jang |
Journal | Annals of hepato-biliary-pancreatic surgery
(Ann Hepatobiliary Pancreat Surg)
Vol. 25
Issue 3
Pg. 349-357
(Aug 31 2021)
ISSN: 2508-5859 [Electronic] Korea (South) |
PMID | 34402435
(Publication Type: Journal Article)
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