Bilateral Breast Ochronosis: a Case Report.

Abstract

Ochronosis is a syndrome characterized by bluish black discoloration due to the deposition of polymerized products of homogentisic acid (HGA) in the connective tissues. The endogenous variety (alkaptonuria), is a rare autosomal recessive metabolic disorder. The disorder is manifested by deficiency of the enzyme homogentisate 1,2-dioxygenase. The characteristic of the condition is a triad of pigmentation of skin, cartilage, and sclera; ochronotic arthropathies and homogentisic aciduria (resulting in darkening of urine). More rarely, it may affect the breast. This rare and interesting case of a woman with ochronosis of both breasts and chest wall, prompted us to write this case report.

• Authors: Fatema A J AbdulKarim, Safwat M Ibrahim, Arnold Ad Hill, Nadeem Ajmal
• Journal: JPRAS open (JPRAS Open) Vol. 30 Pg. 23-28 (Dec 2021) ISSN: 2352-5878 [Electronic] Netherlands
• PMID: 34381863 (Publication Type: Case Reports)
• Copyright: © 2021 The Authors.