[Treatment of urinary infection with cephadroxyl (Pharmachem)--microbiological and clinical research].

Abstract

The bacteria isolated from the urine of renal patients were tested for sensitivity towards cephadroxyl (Pharmachem) and other beta-lactam antibiotics--altogether 654 examinations were made. It was established that the gram-positive bacteria (excluding the Enterococcus) are sensitive towards cephadroxyl. From the Gram negative bacteria E. Coli, Klebsiella sp., Enterobacter sp., P. mirabilis, Citrobacter sp. showed the greatest sensitivity towards cephadroxyl, while the indole positive Proteus were with low sensitivity and P. aeruginosa, Acinetobacter sp., Serratia were resistant towards cephadroxyl. 30 patients with persistent mainly secondary urinary infection were treated with cephadroxyl. The clinical symptoms disappeared in 63.3% of the patients and another 26.7% of them showed considerable improvement. Bacteriological sterility of the urine was achieved in 61.29% of the patients. The side effects were mild and rare, only in single cases.

• Authors: N Minkov, Z Zlatanov, B Zozikov, D Khristova
• Journal: Vutreshni bolesti (Vutr Boles) Vol. 26 Issue 5 Pg. 98-104 ( 1987) ISSN: 0506-2772 [Print] Bulgaria
• Vernacular Title: Lechenie na uroinfektsiiata s tsefadroksil (Farmakhim)--mikrobiologichni i klinichni prouchvaniia.
• PMID: 3433735 (Publication Type: Comparative Study, English Abstract, Journal Article)

Chemical References

• Cefadroxil

Topics

• Adult
• Aged
• Bacteriuria (drug therapy, microbiology)
• Cefadroxil (adverse effects, pharmacology, therapeutic use)
• Female
• Gram-Negative Bacteria (drug effects, isolation & purification)
• Gram-Positive Bacteria (drug effects, isolation & purification)
• Humans
• Male
• Microbial Sensitivity Tests
• Middle Aged
• Urinary Tract Infections (drug therapy, microbiology)