[Muscle relaxant and reversal practices and impact of reversal modalities on operating room and postoperative room duration - results of a Delphi study].

Abstract

OBJECTIVE:

The objectives of this Delphi study are to describe muscle relaxant and reversal practices in France and to seek a consensus on the impact of the reversal method on the time spent in the OR and PACU.

METHOD:

A two-round Delphi survey was conducted on a panel of French anesthetists involved in colectomies, hysterectomies or bariatric surgery. The questionnaire was designed in collaboration with a scientific committee and was intended to assess neuromuscular blockade reversal techniques and their impact on time spent in the OR and PACU. The first round gathered data on practices and the second round sought a consensus for the time aspect.

RESULTS:

Overall, all participants (99%) monitored neuromuscular blockade, with a majority (82%) doing so continuously. Of the participants, 22% routinely used a reversal drug. The time saved in the OR or PACU with sugammadex varied between 1 and 43 minutes depending on the surgery and the neuromuscular blockade reversal method it was compared to.

CONCLUSION:

Although SFAR recommendations (French Society of Anesthesia & Intensive Care Medicine) were generally well followed, the use of neuromuscular blockade reversal drugs was observed to be not fully integrated into regular practice, despite the fact that more than half of patients were reported to have residual neuromuscular blockade post-surgery and that sugammadex is known to reduce time spent in the OR and PACU compared to other neuromuscular blockade reversal methods.

• Authors: J Raft, C Anastasy, E Lambaudie, E Saillio, C Mackosso, N Petrica, C Le Dissez, P Alfonsi
• Journal: Annales pharmaceutiques francaises (Ann Pharm Fr) Vol. 80 Issue 2 Pg. 227-237 (Mar 2022) ISSN: 0003-4509 [Print] France
• Vernacular Title: Pratiques de curarisation/décurarisation et impact des modalités de décurarisation sur les durées en salle opératoire et SSPI – résultats d’une enquête Delphi.
• PMID: 34314682 (Publication Type: Journal Article)
• Copyright: Copyright © 2021. Published by Elsevier Masson SAS.

Chemical References

• Neuromuscular Nondepolarizing Agents
• Pharmaceutical Preparations
• gamma-Cyclodextrins
• Neostigmine

Topics

• Delphi Technique
• Humans
• Muscles
• Neostigmine
• Neuromuscular Blockade (methods)
• Neuromuscular Nondepolarizing Agents
• Operating Rooms
• Pharmaceutical Preparations
• gamma-Cyclodextrins