HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Comparison of ketoconazole and griseofulvin in the treatment of tinea pedis.

Abstract
Twenty-nine patients with mycologically proven tinea pedis were randomly allocated to oral treatment with either ketoconazole 200 mg daily or griseofulvin 1 g daily for a period of up to 8 weeks. Mycological cure rate at 4 weeks was 33% for ketoconazole and 29% for griseofulvin, and at 8 weeks was 53% and 57% respectively. The efficacy of both drugs in the treatment of interdigital tinea pedis is similar, and is considerably lower than that found with topical imidazole preparations where cure rates of over 70% are generally expected.
AuthorsD T Roberts, N H Cox, J C Gentles, K K Babu
JournalJournal of medical and veterinary mycology : bi-monthly publication of the International Society for Human and Animal Mycology (J Med Vet Mycol) Vol. 25 Issue 5 Pg. 347-50 (Oct 1987) ISSN: 0268-1218 [Print] England
PMID3430295 (Publication Type: Clinical Trial, Comparative Study, Journal Article, Randomized Controlled Trial)
Chemical References
  • Griseofulvin
  • Ketoconazole
Topics
  • Double-Blind Method
  • Griseofulvin (therapeutic use)
  • Humans
  • Ketoconazole (therapeutic use)
  • Tinea Pedis (drug therapy)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: