Use of high-density fluorosilicone oil in open-sky vitrectomy.

Abstract

During prolonged open-sky vitrectomy, fluid accumulates in the suprachoroidal and subretinal spaces and the resultant ballooning of the choroid and of the retina interferes with the surgery. Fluorosilicone oil (polymethyl-3,3,3-trifluoropropylsiloxane) with a specific gravity of 1.28 was tested for use as a temporary vitreous substitute during open-sky vitrectomy. After open-sky vitrectomy and bullous retinal detachment in pigmented rabbits, fluorosilicone oil flattened the retina completely in nine of nine eyes, whereas 1% sodium hyaluronate solution flattened the retina completely in only four of nine eyes. The flattening effect of fluorosilicone oil on the retina was also better than that of 1% sodium hyaluronate in an experiment with retinal detachment and giant retinal tear after open-sky vitrectomy.

• Authors: H Chung, J Acosta, M F Refojo, F I Tolentino
• Journal: Retina (Philadelphia, Pa.) (Retina) Vol. 7 Issue 3 Pg. 180-2 ( 1987) ISSN: 0275-004X [Print] United States
• PMID: 3423434 (Publication Type: Comparative Study, Journal Article, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, P.H.S.)

Chemical References

• Dimethylpolysiloxanes
• Silicone Oils
• Silicones
• polymethyl-3,3,3-trifluoropropylsiloxane
• Hyaluronic Acid

Topics

• Animals
• Dimethylpolysiloxanes (administration & dosage)
• Hyaluronic Acid (administration & dosage)
• Rabbits
• Retinal Detachment (surgery)
• Retinal Perforations (surgery)
• Silicone Oils
• Silicones (administration & dosage)
• Vitrectomy (methods)