Evaluation of monoxide film-based dosimeters for surface dose detection in electron therapy.

Abstract

Generally, electron therapy is applied to tumors on or close to the skin surface. However, this causes a variety of skin-related side effects. To alleviate the risk of these side effects, clinical treatment uses skin dosimeters to verify the therapeutic dose. However, dosimeters suffer from poor accuracy, because their attachment sites are approximated with the help of naked eyes. Therefore, a dosimeter based on a flexible material that can adjust to the contours of the human body is required. In this study, the reproducibility, linearity, dose-rate dependence, and percentage depth ionization (PDI) of PbO and HgO film-based dosimeters are evaluated to explore their potential as large-scale flexible dosimeters. The results demonstrate that both dosimeters deliver impressive reproducibility (within 1.5%) and linearity (≥ 0.9990). The relative standard deviations of the dose-rate dependence of the PbO and HgO dosimeters were 0.94% and 1.16% at 6 MeV, respectively, and 1.08% and 1.25% at 9 MeV, respectively, with the PbO dosimeter outperforming the 1.1% of existing diodes. The PDI analysis of the PbO and HgO dosimeters returned values of 0.014 cm (-0.074 cm) and 0.051 cm (-0.016 cm), respectively at 6 MeV (9 MeV) compared to the thimble chamber and R50. Therefore, the maximum error of each dosimeter is within the allowable range of 0.1 cm. In short, the analysis reveals that the PbO dosimeter delivers a superior performance relative to its HgO counterpart and has strong potential for use as a surface dosimeter. Thus, flexible monoxide materials have the necessary qualities to be used for dosimeters that meet the requisite quality assurance standards and can satisfy a variety of radiation-related applications as flexible functional materials.

• Authors: Moo Jae Han, Seung Woo Yang, Sang Il Bae, Young Min Moon, Wan Jeon, Chul Won Choi, Sung Kwang Park, Jin Young Kim
• Journal: PloS one (PLoS One) Vol. 16 Issue 5 Pg. e0251441 ( 2021) ISSN: 1932-6203 [Electronic] United States
• PMID: 34019553 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Mercury Compounds
• Oxides
• Lead
• lead oxide
• mercuric oxide

Topics

• Electrons (therapeutic use)
• Equipment Design
• Film Dosimetry (instrumentation, methods)
• Humans
• Lead (chemistry)
• Mercury Compounds (chemistry)
• Neoplasms (therapy)
• Oxides (chemistry)