[Pulmonary ultrastructural changes following experimental fat embolism in the rabbit (author's transl)].

Abstract

The intravenous injection of triolein in the rabbit, besides general consequences in some viscera (functional ischemic necrosis of the right ventricle, systemic cerebral and kidney embolisms), induces in the lung non specific reactions similar to those observed after other pulmonary agressions. Yet, some peculiarities are observed only in this experimental model: severe and persistent septal oedema due to early endothelial changes; intensive inflammatory response with numerous macrophages. On the other hand, except in zones with epithelio-conjonctive repair process of necrotic foci, the epithelial reaction reduced to a temporary predominance of type 2-pneumonocytes, remains of low intensity.

• Authors: G Chomette, M Auriol
• Journal: Pathologie-biologie (Pathol Biol (Paris)) Vol. 25 Issue 8 Pg. 523-33 (Oct 1977) ISSN: 0369-8114 [Print] France
• Vernacular Title: Modifications pulmonaires ultrastructurales consécutives aux embolies graisseuses expérimentales chez le lapin.
• PMID: 339165 (Publication Type: English Abstract, Journal Article)

Chemical References

• Triolein

Topics

• Animals
• Disease Models, Animal
• Edema
• Embolism, Fat (pathology)
• Inflammation
• Kidney Glomerulus (ultrastructure)
• Lung (pathology, ultrastructure)
• Rabbits
• Time Factors
• Triolein