Abstract | BACKGROUND: Spontaneous or fine-needle aspiration biopsy (FNAB)-induced remission of primary hyperparathyroidism (PHPT) is an extremely rare and generally transient phenomenon. METHODS: A 40-year-old woman with a history of recurrent kidney stones was diagnosed with PHPT (serum calcium, 14.2 mg/dL; parathyroid hormone [PTH], 380 pg/mL). Ultrasonography and scintigraphy findings were consistent with a left enlarged parathyroid. Ultrasound-guided-FNAB cytology of the lesion did not confirm a parathyroid nature. However, levels of PTH within the needle-washing fluid were elevated. RESULTS: After few days, there was evidence of biochemical remission of the hypercalcemia ( calcium, 8.1 mg/dL), and at subsequent follow-up visits, the enlarged parathyroid showed progressive shrinkage with eucalcemia and normalized PTH levels throughout 12 months of follow-up. CONCLUSIONS: Rarely, remission of PHPT may occur after ultrasound-guided-FNAB performed on a hyperfunctioning parathyroid lesion.
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Authors | Pierpaolo Falcetta, Filomena Cetani, Massimo Tonacchera |
Journal | AACE clinical case reports
(AACE Clin Case Rep)
2021 Jan-Feb
Vol. 7
Issue 1
Pg. 75-79
ISSN: 2376-0605 [Electronic] United States |
PMID | 33851026
(Publication Type: Case Reports)
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Copyright | © 2020 AACE. Published by Elsevier Inc. |