Abstract |
We investigated the prevalence and risk factors for frailty among people with HIV (PWH) in rural Uganda (n = 55, 47% male, mean age 44 years). Frailty was defined according to the Fried criteria with self-reported physical activity level replacing the Minnesota Leisure Time Activity Questionnaire. Alternate classifications for physical activity utilized were the sub-Saharan Africa Activity Questionnaire and the International Physical Activity Questionnaire. Eleven participants (19%) were frail. Frail participants were older (p < 0.001), less likely to be on antiretroviral therapy (p = 0.03), and had higher rates of depression (p < .001) and HIV-associated neurocognitive disorder (p = 0.003). Agreement between physical activity measures was sub-optimal. Prevalence of frailty was high among PWH in rural Uganda, but larger sample sizes and local normative data are needed.
|
Authors | Alyssa Vecchio, Gertrude Nakigozi, Noeline Nakasujja, Alice Kisakye, James Batte, Richard Mayanja, Aggrey Anok, Kevin Robertson, Maria J Wawer, Ned Sacktor, Leah H Rubin, Deanna Saylor |
Journal | Journal of neurovirology
(J Neurovirol)
Vol. 27
Issue 3
Pg. 487-492
(06 2021)
ISSN: 1538-2443 [Electronic] United States |
PMID | 33788138
(Publication Type: Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't)
|
Chemical References |
|
Topics |
- Activities of Daily Living
(psychology)
- Adult
- Aged
- Anti-HIV Agents
(therapeutic use)
- Antiretroviral Therapy, Highly Active
- Cross-Sectional Studies
- Depression
(complications, drug therapy, epidemiology, physiopathology)
- Exercise
(physiology)
- Female
- Frailty
(complications, drug therapy, epidemiology, physiopathology)
- HIV Infections
(complications, drug therapy, epidemiology, physiopathology)
- Humans
- Male
- Middle Aged
- Neurocognitive Disorders
(complications, drug therapy, epidemiology, physiopathology)
- Prevalence
- Risk Factors
- Rural Population
- Surveys and Questionnaires
- Uganda
(epidemiology)
|