Abstract | BACKGROUND AND PURPOSE: New remedies are required for the treatment of neuropathic pain due to insufficient efficacy of available therapies. This study provides a novel approach to develop painkillers for chronic pain treatment. EXPERIMENTAL APPROACH: KEY RESULTS: CONCLUSION AND IMPLICATIONS:
|
Authors | Rana Muhammad Shoaib, Khalil Ali Ahmad, Yong-Xiang Wang |
Journal | British journal of pharmacology
(Br J Pharmacol)
Vol. 178
Issue 15
Pg. 2976-2997
(08 2021)
ISSN: 1476-5381 [Electronic] England |
PMID | 33786848
(Publication Type: Journal Article)
|
Copyright | © 2021 The British Pharmacological Society. |
Chemical References |
- Glucocorticoids
- Receptors, Glucocorticoid
- Sapogenins
- Dynorphins
- protopanaxadiol
|
Topics |
- Animals
- Dynorphins
- Glucocorticoids
- Hyperalgesia
- Microglia
- Neuralgia
(drug therapy)
- Rats
- Rats, Wistar
- Receptors, Glucocorticoid
- Sapogenins
- Spinal Cord
|