Short-term Prognostic Value of Tumor Diameter in Stage 2 and 3 Gastric Cancer.

Abstract

OBJECTIVE:

To investigate the prognostic value of tumor diameter in the short term of 3 and 5 years in patients operated for gastric cancer.

STUDY DESIGN:

A descriptive study.

PLACE AND DURATION OF STUDY:

Kartal Dr Lütfi Kırdar City Hospital, Istanbul, Turkey, from January 2014 to December 2018 Methodology: A total of 125 patients with stage 2 or 3 gastric cancer, followed up in the Department of General Surgery, were included. Demographic information, clinical, laboratory, and pathology reports were analysed in terms of postoperative 30-day mortality.

RESULTS:

The mean age of the patients was 63.9±11.9 (31-88) years. Forty-four (35.2%) were in stage 2, and 81 (64.8%) were in stage 3 cancers. The mean tumor diameter was 6.5±3.1 cm, and the mean metastatic lymph node rate was 35.6±29.8%. The mean follow-up period was 31.8±21 months. The 3-year and 5-year survival rates were 39.8% and 17.6%, respectively. Tumor diameter was not directly related to survival, differentiation, number of resected lymph nodes, number of metastatic lymph nodes, and metastatic lymph node rate in stage 2 and 3 cases (p>0.05 for each). The 5-year mortality risk was 1.2-fold higher in those with tumor diameter over 6.5 cm (95% CI 0.7-2.0; p=536).

CONCLUSION:

The tumor size did not have a direct effect on prognosis. It did not provide reliable data about short-term prognosis such as 3 and 5 years in stage 2 and 3 gastric cancer cases. Key Words: Gastric cancer, Stage 2, Stage 3, Tumor size, Prognosis.

• Authors: Hakan Uzunoglu, Selcuk Kaya
• Journal: Journal of the College of Physicians and Surgeons--Pakistan : JCPSP (J Coll Physicians Surg Pak) Vol. 31 Issue 3 Pg. 288-293 (Mar 2021) ISSN: 1681-7168 [Electronic] Pakistan
• PMID: 33775017 (Publication Type: Journal Article)

Topics

• Aged
• Gastrectomy
• Humans
• Lymph Node Excision
• Lymph Nodes (pathology)
• Middle Aged
• Neoplasm Staging
• Prognosis
• Retrospective Studies
• Stomach Neoplasms (pathology, surgery)
• Survival Rate
• Turkey (epidemiology)