Abstract |
There is now a growing body of clinical evidence suggesting a therapeutic approach to cancer and prostatic hypertrophy by using hyperthermia. It is proposed that such a hyperthermic modality can produce thermal synovectomy in inflammatory arthritis. Heating the joint cavity up to 42 deg C can inhibit the enzymatic effect of collagenase, oxygenase, and other enzymes playing a role in the inflammatory process. If this hypothesis is correct, therapeutic intervention using hyperthermia may offer hope for the treatment of isolated inflammatory joint diseases.
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Authors | A Weinberger, R Fadilah, A Lev, A Levi, J Pinkhas |
Journal | Medical hypotheses
(Med Hypotheses)
Vol. 25
Issue 4
Pg. 231-3
(Apr 1988)
ISSN: 0306-9877 [Print] United States |
PMID | 3367814
(Publication Type: Journal Article)
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Chemical References |
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Topics |
- Arthritis
(physiopathology, therapy)
- Body Temperature
- Cell Division
- Hot Temperature
- Humans
- Hyaluronic Acid
(biosynthesis)
- Hyperthermia, Induced
- Models, Biological
- Pain
(physiopathology)
- Peripheral Nerves
(physiopathology)
- Synovial Membrane
(blood supply, metabolism)
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