All patients with
hereditary angioedema (HAE) must have access to on-demand
therapy to treat attacks and may benefit from prophylactic
therapy to reduce the attack frequency. Treatment decisions should be individualized, based on patient preferences and needs. One method for facilitating individualized
therapy is shared decision-making (
SDM), a widely used methodology for making treatment decisions among multiple therapeutic options. We propose a three-phase "3D" model (Discover, Discuss, Decide) for
SDM in HAE. The Discover phase focuses on improving the physician's understanding of the patient's needs and understanding of the available therapeutic choices. The Discuss phase considers the alternatives, allowing a collaborative, informed treatment selection in the Decision phase. The 3D model is an ongoing, iterative process based on the patient's changing needs and response to
therapy. Uncovering the patient's
therapy goals through appropriate questions during these phases can help uncover relevant information for treatment selection information.
SDM based on the 3D model can be a beneficial tool for optimizing
therapy in HAE.