Induction of ovulation with cyclophenyl.

Abstract

The results of 495 cycles of treatment with Cyclophenyl given to 286 women suffering from amenorrhea, oligomenorrhea or persistent anovulation are reported. In 61 cases the drug solved the problems of infertility, with a success rate of 43%. The over-all success rate was 58% (288 ovulatory cycles produced in 495 treatment cycles). In detail:--in cases of prolonged amenorrhea, with plasma estradiol levels lower than 50 pg/ml, the positive results were only 15%;--in cases of short-term amenorrhea, with plasma estradiol levels lower than 50 pg/ml, the success rate was only 18%;--in cases with prolonged amenorrhea but with plasma estradiol levels higher than 50 pg/ml, the success rate was 43%;--in cases of short-term amenorrhea with plasma estradiol levels higher than 50 pg/ml, the success rate was 68%;--in cases of oligomenorrhea and of persistent anovulation, the success rate was 72%.

• Authors: C Melega, V M Jasonni, A Di Leo, S Venturoli, G Fuschini, C Flamigni
• Journal: Acta Europaea fertilitatis (Acta Eur Fertil) Vol. 8 Issue 2 Pg. 119-32 (Jun 1977) ISSN: 0587-2421 [Print] Italy
• PMID: 335763 (Publication Type: Clinical Trial, Comparative Study, Journal Article)

Chemical References

• Chorionic Gonadotropin
• Cresols
• Estradiol
• Cyclofenil

Topics

• Amenorrhea (drug therapy)
• Anovulation (drug therapy)
• Chorionic Gonadotropin (therapeutic use)
• Clinical Trials as Topic
• Cresols (therapeutic use)
• Cyclofenil (therapeutic use)
• Drug Evaluation
• Estradiol (blood)
• Female
• Humans
• Infertility, Female (drug therapy)
• Oligomenorrhea (drug therapy)
• Ovulation
• Ovulation Induction
• Pregnancy