Abstract | BACKGROUND: METHODS: Fourteen patients with ICC underwent CT (Plain and Portal, CT scans before and 70 s after the injection of Omnipaque, respectively), DWI, and Gd-EOB-DTPA-enhanced MRI (EOB 70 s and EOB 15 min, mDIXON scans at 70 s and 15 min after the injection of Gd-EOB-DTPA, respectively) examinations before radiotherapy. Volumes of GTV delineation on CT and MRI images were recorded. Dice similarity coefficient (DSC) was calculated to evaluate the spatial overlap. RESULTS:
Tumor volume on DWI and EOB 15 min were larger than that on EOB 70 s significantly (both P=0.004). DSC of DWI was significantly larger than that of other CT and MRI sequences (all P≤0.002). DSC of EOB 15 min tended to be larger than that of other CT sequences and EOB 70 s, however, without significances (all P>0.005). Significant correlation was found between DSC and tumor volume (R=0.35, P=0.003). CONCLUSIONS: DWI had significantly higher agreement on GTV delineation of ICC. GTV delineations of ICC on Gd-EOB-DTPA-enhanced MRI showed excellent inter-observer agreement. Fusion of CT and MRI images should be considered to improve the accuracy of GTV delineation.
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Authors | Nan Zhou, Anning Hu, Zhihao Shi, Xiaolu Wang, Qiongjie Zhu, Qun Zhou, Jun Ma, Feng Zhao, Weiwei Kong, Jian He |
Journal | Quantitative imaging in medicine and surgery
(Quant Imaging Med Surg)
Vol. 11
Issue 2
Pg. 579-585
(Feb 2021)
ISSN: 2223-4292 [Print] China |
PMID | 33532258
(Publication Type: Journal Article)
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Copyright | 2021 Quantitative Imaging in Medicine and Surgery. All rights reserved. |