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Antibacterial activity of recombinant murine beta interferon.

Abstract
Recombinant murine beta interferon was protective and therapeutic for mice against Listeria monocytogenes infection in vivo. The recombinant murine beta interferon caused enhanced H2O2 release by macrophages in vivo, but not in vitro.
AuthorsT Fujiki, A Tanaka
JournalInfection and immunity (Infect Immun) Vol. 56 Issue 3 Pg. 548-51 (Mar 1988) ISSN: 0019-9567 [Print] United States
PMID3343048 (Publication Type: Journal Article)
Chemical References
  • Interferon Type I
  • Recombinant Proteins
  • Hydrogen Peroxide
Topics
  • Animals
  • Hydrogen Peroxide (metabolism)
  • Immunotherapy
  • Interferon Type I (therapeutic use)
  • Listeriosis (prevention & control, therapy)
  • Liver (microbiology)
  • Macrophage Activation
  • Macrophages (metabolism)
  • Mice
  • Recombinant Proteins (therapeutic use)
  • Spleen (microbiology)

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