[Use of carminomycin on adult patients with acute leukemias].

Abstract

The data on the clinical trials of karminomycin, a new antitumor antibiotic are presented. The drug was used in the treatment of 46 adult patients with leukemia. Karminomycin was used in primary inducing therapy and treatment of relapses. The results of the trials showed that karminomycin had a definite therapeutic activity in treatment of acute myeloblast leukemia at various stages of the process. A rapid effect of the antibiotic provided its use in emergency cases with rapidly progressing variants of the disease.

• Authors: F E Faĭnshteĭn, L G Kovaleva, M V Vakhrusheva, V G Isaev, E M Abakumov
• Journal: Antibiotiki (Antibiotiki) Vol. 22 Issue 8 Pg. 756-8 (Aug 1977) ISSN: 0003-5637 [Print] Russia (Federation)
• Vernacular Title: Primenenie karminimitsina u vroslykh bol'nykh ostrymi leĭkozami.
• PMID: 334058 (Publication Type: Clinical Trial, Comparative Study, English Abstract, Journal Article)

Chemical References

• Antibiotics, Antineoplastic
• Carubicin
• Daunorubicin

Topics

• Adult
• Antibiotics, Antineoplastic (administration & dosage)
• Bone Marrow (drug effects)
• Carubicin (administration & dosage)
• Clinical Trials as Topic
• Daunorubicin (therapeutic use)
• Drug Evaluation
• Drug Tolerance
• Humans
• Leukemia, Lymphoid (drug therapy)
• Leukemia, Myeloid, Acute (drug therapy)
• Time Factors